Mangosteen peel (Garcinia mangostana L.) is the thick purple rind of the mangosteen fruit, a tropical evergreen tree belonging to the Clusiaceae (Guttiferae) family. Native to Southeast Asia, particularly Indonesia, Malaysia, and Thailand, mangosteen has long been valued in traditional medicine. The peel is especially rich in xanthones (primarily α-mangostin and γ-mangostin), flavonoids, tannins, anthocyanins, polyphenols, and other phenolic compounds. These bioactive constituents exhibit strong antioxidant, anti-inflammatory, antimicrobial, and pharmacological activities, making mangosteen peel an important raw material for pharmaceutical research and herbal medicine development.
Sumber: Halodoc
Applications and Benefits in the Pharmaceutical Industry
- Used in antioxidant formulations to help protect cells from oxidative stress and free radical damage.
- Incorporated into anti-inflammatory products for the management of inflammatory conditions.
- Studied for its antimicrobial and antifungal properties against various pathogenic bacteria and fungi.
- Investigated for its potential anticancer activity, particularly the role of xanthones in inhibiting cancer cell growth.
- Utilized in cardiovascular health formulations due to its antioxidant and anti-inflammatory effects.
- Explored for its antidiabetic potential by supporting healthy glucose metabolism.
- Investigated for neuroprotective properties, which may help protect nerve cells from oxidative damage.
- Used in wound healing and dermatological formulations because of its antimicrobial and tissue-protective effects.
- Studied for its hepatoprotective effects, supporting liver function and protecting against oxidative injury.
- Continues to be researched as a source of natural bioactive compounds for the development of innovative pharmaceutical and nutraceutical products.
