BROTOWALI (BITTER GRAPE) EXTRACT

Brotowali (Tinospora crispa) is a medicinal plant that has long been used in traditional medicine throughout Southeast Asia, particularly in Indonesia, Malaysia, and Thailand. Known for its distinctive bitter taste, brotowali has been utilized for centuries to support general health and to help manage various ailments. Owing to its medicinal properties, brotowali has attracted considerable attention in the fields of traditional medicine, pharmaceuticals, food and beverages, dietary supplements, and, to a lesser extent, cosmetics.

Brotowali belongs to the Menispermaceae family and is characterized by its climbing stems, heart-shaped leaves, and rough, warty bark. The stems are the most commonly used part of the plant because they contain numerous bioactive compounds. Traditionally, brotowali has been consumed as herbal decoctions and extracts to help relieve fever, support blood sugar regulation, improve digestion, and strengthen the immune system.

                                                             Image Courtesy : halodoc.com

Furthermore, brotowali contains a wide range of bioactive compounds, including alkaloids, flavonoids, glycosides, diterpenoids, terpenoids, phenolic compounds, and berberine. These compounds exhibit antioxidant, anti-inflammatory, antidiabetic, antimicrobial, hepatoprotective, and immunomodulatory activities that help protect the body from oxidative stress and cellular damage. Due to its diverse chemical composition and biological properties, brotowali continues to be cultivated and utilized as an important ingredient in herbal medicines, functional foods, and health supplements.

The benefits of brotowali include:

Traditional Medicine

  • Herbal remedies and traditional medicines (jamu): Brotowali has long been used to help relieve fever, digestive disorders, joint pain, and fatigue.
  • Natural therapeutic agent: Its bioactive compounds may help regulate blood sugar levels and support the immune system.
  • Traditional herbal preparations: Brotowali is commonly processed into herbal decoctions and extracts to promote overall health and vitality.

Pharmacy

  • Herbal capsules and syrups: Brotowali extract is incorporated into pharmaceutical products because of its antidiabetic, anti-inflammatory, and antioxidant properties.
  • Source of bioactive compounds: Active compounds such as berberine and flavonoids are studied for the development of herbal medicines.
  • Therapeutic formulations: Brotowali is used in formulations intended to support liver health, metabolic function, and immunity.

Supplement 

  • Capsules and powdered supplements: Brotowali is widely processed into dietary supplements to support immunity and overall health.
  • Metabolic health products: Its active compounds may help maintain blood sugar balance and support liver function.
  • Wellness supplements: Brotowali is commonly incorporated into supplements intended to maintain vitality and promote general well being.